Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/252150040?client_source=feed&format=rss
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LOS ANGELES (AP) ? Adam Sandler's monster mash-up "Hotel Transylvania" has brought the weekend box office back to life after a late-summer slump.
The animated comedy from Sony Pictures debuted at No. 1 with $43 million, one of the strongest starts ever for a movie opening in September, according to studio estimates Sunday.
"Hotel Transylvania" set a new high for September debuts in terms of actual dollars, beating the previous record of $35.7 million for 2002's "Sweet Home Alabama." But factoring in today's higher admission prices, "Sweet Home Alabama" sold more tickets.
This weekend's box office was further strengthened by a solid No. 2 debut for another Sony release, Bruce Willis and Joseph Gordon-Levitt's time-travel thriller "Looper," which took in $21.2 million.
Hollywood's overall grosses rose for the first time in a month compared to the same weekend last year. Revenues totaled $120 million, up 21 percent from the same weekend a year ago, when "Dolphin Tale" led with $13.9 million, according to box-office tracker Hollywood.com.
"Sony really kind of saved the day here, turning things around after a full month of less-than-stellar box office," said Hollywood.com analyst Paul Dergarabedian. "The post-summer period didn't exactly set the world on fire."
It's rare for one studio to open two wide releases over the same weekend, but Sony had two movies that complemented each other well without overlapping their audiences.
Locking up the family crowds, the PG-rated "Hotel Transylvania" features Sandler providing the voice of Count Dracula as proprietor of a resort catering to Frankenstein, the Wolfman and other monsters.
The R-rated "Looper" pulled in male action fans. Set in 2044, the film stars Gordon-Levitt as a hit man assigned to kill victims sent back in time ? including his future self (Bruce Willis).
The previous weekend's No. 1 movie, Open Road Films' police story "End of Watch," fell to No. 3 with $8 million, raising its domestic total to $26.2 million.
In narrower release, Universal Pictures' music tale "Pitch Perfect" opened strongly at No. 6 with $5.2 million. The movie stars Anna Kendrick as a college freshman who joins an a cappella singing team and livens up the group's conservative style.
Playing in 335 theaters, "Pitch Perfect" averaged an impressive $15,560 a cinema. That compared to an average of $12,840 in 3,349 theaters for "Hotel Transylvania" and $7,086 in 2,992 cinemas for "Looper."
The weekend's other new wide release, Maggie Gyllenhaal and Viola Davis' school drama "Won't Back Down," flopped at No. 10 with $2.7 million, averaging just $1,074 in 2,515 theaters. The movie centers on two mothers who organize a campaign to save a failing elementary school.
For Sandler, "Hotel "Transylvania" was a return to hit status after his summer dud "That's My Boy" and so-so results on last year's comedy "Jack and Jill."
Sandler's audience of young males generally has waned as he ages. But Sony, which has released most of his movies, remains eager to stay in the Sandler business.
"I have said that many times, and it still holds in a big way," said Rory Bruer, head of distribution for Sony.
Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers are also included. Final domestic figures will be released Monday.
1. "Hotel Transylvania," $43 million ($8.1 million international).
2. "Looper," $21.2 million ($8.5 million international).
3. "End of Watch," $8 million.
4. "Trouble with the Curve," $7.5 million.
5. "House at the End of the Street," $7.2 million ($1.5 million international).
6. "Pitch Perfect," $5.2 million.
7. "Finding Nemo," $4.1 million ($1.1 million international).
8. "Resident Evil: Retribution," $3 million ($20.7 million international).
9. "The Master," $2.75 million.
10. "Won't Back Down," $2.7 million.
___
Estimated weekend ticket sales at international theaters (excluding the U.S. and Canada) for films distributed overseas by Hollywood studios, according to Rentrak:
1. "Resident Evil: Retribution," $20.7 million.
2. "Ted," $9.1 million.
3 (tie). "Masquerade," $9 million.
3 (tie). "Les Seigneurs," $9 million.
5. "Ice Age: Continental Drift," $8.7 million.
6. "Looper," $8.5 million.
7. "Hotel Transylvania," $8.1 million.
8. "The Bourne Legacy," $7.7 million.
9. "Taken 2," $6.4 million.
10. "Madagascar 3: Europe's Most Wanted," $6.1 million.
___
Online:
http://www.hollywood.com
http://www.rentrak.com
___
Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.
Source: http://news.yahoo.com/hotel-transylvania-checks-43m-debut-154646517--finance.html
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TEHRAN (AP) ? Iranian officials announced that they would soon introduce local alternatives to Google and its Gmail e-mail service, even as the country's media and even some officials stepped up complaints over Tehran's decision to enact a ban on Gmail in response to an anti-Islam film, newspapers reported on Sunday.
Last week, Iran blocked Gmail -- but not the search engine of the parent company Google -- in response to a court order linked to the distribution of a low-budget, U.S.-produced film on YouTube, also owned by Google.
In a country with 32 million Internet users out of a population of 75 million, according to official statistics, that ban has caused widespread resentment. Even many pro-government newspapers have complained of the disruptions.
"Some problems have emerged through the blocking of Gmail," Hussein Garrousi, a member of a parliamentary committee on industry, was quoted Sunday by the independent Aftab daily as saying. He said that parliament would summon the minister of telecommunications for questioning if the ban was not lifted.
The deputy minister, Ali Hakim Javadi, told reporters that Iranian authorities were considering lifting the Gmail ban, but also wanted to introduce their own domestic alternatives: the Fakhr ("Pride") search engine and the Fajr ("Dawn") e-mail services, Aftab reported.
Iran's clerical establishment has long signaled its intent to get citizens off of the international Internet, which they say promotes Western values, and onto a "national" and "clean" domestic network. But it is unclear whether Iran has the technical capacity to follow through on its ambitious plans, or is willing to risk the economic damage.
Bans on Gmail and other services like YouTube and Facebook have left Internet users scrambling to find ways to bypass the blocks.
On Saturday, Asr-e Ertebat weekly reported that Iranians had paid a total of 4.5 million US dollars to purchase proxy services to reach blocked sites over the past month.
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(Reuters) - UBS AG
U.S. District Judge Richard Sullivan in Manhattan issued the ruling. The case is dismissed with prejudice, meaning the plaintiffs cannot replead their case at the district court level.
"Although UBS made a series of bad bets with disastrous consequences for the company and its shareholders, those consequences alone are insufficient to establish and support a claim for securities fraud," Sullivan wrote.
Karina Byrne, a UBS spokeswoman, said the bank "is pleased with Judge Sullivan's well-reasoned decision dismissing the complaint with prejudice."
Lawyers for the plaintiffs did not immediately respond to requests for comment.
The lawsuit, filed in 2007, spilled out of UBS's subprime mortgage losses during the height of the financial crisis. UBS wrote down $48.6 billion in assets between 2007 and 2009 due to its investments in mortgage-backed securities that went sour, according to the complaint.
The lawsuit accused UBS of violating U.S. securities laws by issuing fraudulent statements related to its mortgage-related and auction rate securities portfolios.
The plaintiffs also claimed UBS misled investors by engaging in a scheme in which its Swiss bankers helped U.S. clients engage in tax evasion. UBS ultimately in 2009 agreed to a $780 million settlement with the U.S. government to settle its criminal probe.
But Sullivan said the plaintiffs had failed to put forward a case that UBS had acted with intent to defraud investors. The judge separately said the investors had failed to allege that any mistatements or omissions related to its private banking business were material.
The lead plaintiff in the case was the City of Pontiac Policemen's and Firemen's Reitrement System. An earlier decision by Sullivan had limited the class to investors who had not bought UBS shares on foreign stock exchanges.
The case is In re UBS AG Securities Litigation, U.S. District Court for the Southern District of New York, 07-cv-11225
(Reporting By Nate Raymond in New York; Editing by Gerald E. McCormick and Kenneth Barry)
Source: http://news.yahoo.com/ubs-wins-dismissal-shareholder-lawsuit-185158905--finance.html
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California became the first state to explicitly block universities and employers from seeking access to applicants' social media accounts, as Gov. Jerry Brown signed two measures Sept. 27, reported The Sacramento Bee. Under the new laws, employers are not allowed to fire or discipline workers who refuse to share information related to their social media accounts, such as passwords.
"The Golden State is pioneering the social media revolution and these laws will protect all Californians from unwarranted invasions of their personal social media accounts," Brown said in a prepared statement.
University students in California, athletes in particular, are now also protected from anyone requesting access to their social media accounts or personally identifiable information that could link a student to an online profile.
?Employers have no right to ask job applicants for their house keys or to read their diaries ? why should they be able to ask them for their Facebook passwords and gain unwarranted access to a trove of private information about what we like, what messages we send to people, or who we are friends with?? said Charles E. Schumer, a New York senator who has requested that the Federal Trade Commission create such a regulation since 2010.
Before passage of the new laws, Facebook issued multiple statements discouraging employers or universities from prying into users' accounts. ?While we do not have any immediate plans to take legal action against any specific employers, we look forward to engaging with policymakers and other stakeholders, to help better safeguard the privacy of our users,? a Facebook statement reads.
The laws, based on AB 1844 and SB 1349, will go into effect Jan. 1.
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Sweet Sweat, the world-renowned scientifically-tested thermogenic workout enhancer, will be one of the participants in the upcoming Mr. Olympia Trade Show that will be held at the Las Vegas Convention Center in Las Vegas, Nevada on September 27 and 30. Coinciding with this big event is the launch of their newest supplement SVETOL Green Coffee Bean Extract ? an all-natural fitness supplement with virgin coconut oil-infused soft gels. Team Sweet Sweat will also do live product demonstrations at booth number 1312.
Los Angeles, California (PRWEB) September 27, 2012
Sweet Sweat, the world-renowned scientifically-tested topical thermogenic workout enhancer from Sports Research, will be one of the many participants in the upcoming Mr. Olympia Trade Show that will be held at the Las Vegas Convention Center in Las Vegas, Nevada on September 29 and 30, 2012. Coinciding with this huge event is the launch of Sports Research Corporation?s newest supplement, SVETOL Green Coffee Bean Extract. This latest line of fitness supplements from the California-based company has all-natural ingredients sealed by virgin coconut oil-infused soft gels, making it truly one of a kind.
This year?s Mr. Olympia Trade Show will be held on September 29-30, 2012 in Las Vegas, Nevada. Over 750 booths will be featuring top fitness products, supplements, and apparel from all over the world. Attendees will also get their chance to get free samples, purchase new products, and meet celebrities, athletes, and other sports and fitness icons. What?s more, team Sweet Sweat will also be doing live product demonstrations at booth number 1312. The Las Vegas Convention Center will be filled with eager fitness enthusiasts and throngs of attendees as highly anticipated events like the 212 Showdown, Bikini Olympia, Ms. Olympia, and more, are expected to take place.
?We?re thrilled to be participating in this huge event. Renowned bodybuilders and fitness enthusiasts from all over the country, including those from overseas, are expected to be there. What?s even more exciting is that we get to launch our newest weight loss supplement, the SVETOL Green Coffee Bean Extract. It?s an all-natural supplement that?s unique because its liquid formula is sealed in soft gels infused with virgin coconut oil. We?ll also be doing live product demos to show people how highly effective our products are. People will really get to see how Sweet Sweat actually works,? said Jeff Pedersen Jr., Sweet Sweat?s Vice-President for Sales and Marketing.
The product demo will involve a member of Team Sweet Sweat applying the thermogenic workout enhancer on one side of his or her body before jumping rope in front of a thermographic camera. The camera will then reveal how Sweet Sweat works by showing infrared heat patterns demonstrating increased blood circulation in the areas where Sweet Sweat was applied.
Aside from live product demonstrations, Team Sweet Sweat will also be giving out helpful tips to teach health-conscious people what to look for when buying green coffee bean extract with SVETOL. Looking for the term ?SVETOL? or ?GCA? on the label is a great example. ?Our SVETOL Green Coffee Bean extract actually has the same formula recommended by Dr. Oz. It has 45 percent chlorogenic acid, zero fillers, zero binders, and zero artificial ingredients. It basically helps with natural weight management and glucose control among others,? added Pedersen.
For more information about Sweet Sweat or any of Sports Research?s products, visit http://www.sweetsweat.com/, email info(at)sweetsweat(dot)com, or call +8006339308.
About Sweet Sweat:
Sweet Sweat was developed by fitness expert Jeff Pedersen, Sr., the first baseball player in NCAA history to start on three straight national champion teams. The elder Pedersen launched Sweet Sweat in 1980, and Sweet Sweat products are now available in 54 countries worldwide. Sweet Sweat is manufactured by Sports Research, a California-based company that also produces dietary supplements and other fitness products.
For the original version on PRWeb visit: http://www.prweb.com/releases/prweb2012/9/prweb9952871.htm
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This photo taken Sept. 27, 2012 shows President Barack Obama waving as he walks from the Oval Office of the White House in Washington. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/Carolyn Kaster)
This photo taken Sept. 27, 2012 shows President Barack Obama waving as he walks from the Oval Office of the White House in Washington. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/Carolyn Kaster)
In this photo taken Sept. 27, 2012, Republican presidential candidate, former Massachusetts Gov. Mitt Romney speaks in Springfield, Va. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/ Evan Vucci)
FILE - In this Sept. 8, 2012 file photo, Sen. John McCain, R-Ariz. is interviewed in Cernobbio, Italy. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/Giuseppe Aresu, File)
FILE - This Aug. 28, 2012 file photo shows Republican National Committee Reince Priebus speaking at the Republican National Convention in Tampa, Fla. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/Charlie Neibergall, File)
FILE - This Aug. 30, 2012 file photo shows US United Nations Ambassador Susan Rice speaking at the United Nations. Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing. (AP Photo/Bebeto Matthews, File)
WASHINGTON (AP) ? Republicans lashed out at President Barack Obama and senior administration officials over their evolving description of the deadly Sept. 11 attack on the U.S. Consulate in Libya, a late campaign-season broadside challenging the veracity and leadership of an incumbent on the upswing.
Desperate to reverse the apparent trajectory of the White House race, Republicans sense a political opportunity in Obama's reluctance to utter the words "terrorist attack" as well as the varying explanations emerging from the administration about the assault in Benghazi that killed Ambassador Chris Stevens and three other Americans.
Talk of Watergate-style scandal, stonewalling and cover-up echoed in the GOP ranks on Thursday, from the head of the party to members of Congress to Mitt Romney's campaign staff. This full-throated criticism comes five days before the first debate between Obama and Romney, with Republicans determined to cast the president as dishonest and ineffectual on both foreign and domestic policy.
"Amid Middle East turmoil and six weeks before the election, President Obama refuses to have an honest conversation with the American people," Reince Priebus, chairman of the Republican Party, wrote in an article for the website Real Clear Politics. "The country deserves honesty, not obfuscation, from our president."
Republicans say the administration has been slow to call the assault a terrorist attack and has criticized its initial insistence that the attack was a spontaneous response to the crude anti-Islam video that touched off demonstrations across the Middle East.
Since then, it has become clear that the Benghazi assault was distinct from the mobs that burned American flags and protested what they considered the blasphemy in the movie, but didn't attack U.S. personnel. Republicans have also suggested that the administration had intelligence suggesting the deadly attack might happen and ignored it.
"I think it's pretty clear that they haven't wanted to level with the American people. We expect candor from the president and transparency," Romney told Fox News this week.
The White House and Democrats accused the GOP of politicizing national security, with officials specifically mentioning Romney's quick swipe at Obama as an extremist sympathizer as the crisis was still unfolding in North Africa around Sept. 11.
"The Republican approach is to shoot first and ask questions later," Rep. Adam Smith of Washington state, the top Democrat on the House Armed Services Committee, said in an interview. "The administration wants to do an investigation and be as accurate as possible. That's the difference between partisan politics and trying to govern."
Democrats also used the criticism to recall the former Massachusetts governor's missteps during his summertime overseas trip and his omission in his prime-time speech at the Republican National Convention of any mention of U.S. military forces fighting in Afghanistan.
"Every time Mitt Romney has attempted to dip his toe into foreign policy quarters, it's been an unmitigated disaster," Obama campaign press secretary Jen Psaki said aboard Air Force One.
National security has provided few political openings for Romney and the GOP as Obama has shed the Democrats' past reputation for weakness by ordering the successful raid that killed terrorist leader Osama bin Laden and undercut al-Qaida. An Associated Press-GfK poll earlier this month found Obama with an edge over Romney on who Americans think can do a better job of protecting the country, 51 percent to 40 percent.
The economy and jobs are the dominant issues in the election, with few voters likely to cast their ballots based on events in Libya or conflicts overseas. Underscoring the general weariness after more than 10 years of war, some of the fiercest GOP defense hawks in Congress have suggested the United States withdraw its forces from Afghanistan, an even bolder step than Obama.
But the administration has struggled to present a coherent description of the assault in Libya, prompting questions from Republicans and Democrats about whether the United States had prior intelligence, whether the attack was planned and whether security was sufficient.
In that same AP poll, Americans approved of Obama's handling of Libya by just 45-41 percent. The poll was conducted within days of the assault.
Defense Secretary Leon Panetta on Thursday called it a terrorist attack.
"What terrorists were involved I think still remains to be determined by the investigation," he told reporters at the Pentagon. "But it clearly was a group of terrorists who conducted that attack."
Secretary of State Hillary Rodham Clinton and White House press secretary Jay Carney called the violence a terrorist attack last week. But Obama has declined several chances to call the incident a terrorist attack. He said last week that extremists used an anti-Islam video as an excuse to assault U.S. interests.
And just five days after the attack, U.S. Ambassador to the United Nations Susan Rice said the attack was a spontaneous reaction to the video. Her assessment was at odds with Libya's interim President Mohammed el-Megarif, who said there was no doubt the perpetrators had predetermined the date of the assault. Panetta said Thursday it was a "planned attack."
The FBI is investigating, but the apparent contradictions have prompted demands for information from Congress and a flurry of scathing letters to the administration.
So far, U.S. intelligence has indicated that heavily armed extremists numbering 50 or more attacked the consulate, relying on gun trucks for added firepower. They established a perimeter, limiting access to the compound. A first wave of attacks forced the Americans to flee to a fallback building, where a second group of extremists attacked with mortar fire. Stevens died of apparent smoke inhalation when he was caught inside one of the consulate buildings, which had been set on fire.
Officials have not singled out one responsible group, but have focused their attention on Ansar al-Shariah, a Libyan militant group led by a former detainee at the U.S. military-run prison in Guantanamo Bay, Cuba.
Gen. Martin Dempsey, chairman of the Joint Chiefs of Staff, said Thursday that there has been a "thread of intelligence reporting" about groups in eastern Libya trying to coalesce, but no specific threat to the consulate.
Since the fall of Libyan leader Moammar Gadhafi last year, militias, weapons and terrorists are common in Libya.
"It was just unbelievable that Ambassador Rice and Secretary Clinton and the White House spokesman and others would say that there was no evidence ? that this was a spontaneous attack, yet they say, 'come on, honey, bring your mortars, we're going to a spontaneous demonstration,'" Sen. John McCain, R-Ariz., said on CBS' "This Morning."
McCain, who called the administration's statements "disgraceful," joined three other Republican senators this week in a letter to Rice pressing her on her "troubling statements that are inconsistent with the facts."
Eight Republicans who head House committees sent a letter to Obama criticizing a "pre-9/11 mindset" of "treating an act of war solely as a criminal matter." They said they would return to Washington from their nearly two-month recess for briefings beyond the back-to-back sessions Clinton and others held last week.
Sens. Bob Corker, R-Tenn., and Johnny Isakson, R-Ga., have asked for communications between the State Department and the U.S. mission in Libya leading up to the attacks.
Senate Foreign Relations Committee Chairman John Kerry, D-Mass., has written the State Department's Thomas Nides asking him to provide the panel with a detailed accounting of the attacks on U.S. missions in Libya, Egypt and Yemen on Sept. 11, information on security and whether there was any prior intelligence.
Sen. Chris Coons, D-Del., a member of the panel, said the purpose of this letter is a bipartisan effort to get information.
"I do think it is legitimate and appropriate to ask questions," Coons said in an interview. "Some have sadly overreached and clearly are politicizing this incident."
___
Associated Press writers Robert Burns in Washington and Steve Peoples in Springfield, Va., contributed to this report.
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ATHENS (Reuters) - Greek political leaders are still haggling over the details of 12 billion euros worth of budget cuts needed to release further tranches of its international bailout, government officials said on Thursday.
Officials, declining to be named, had told Reuters on Wednesday that the Prime Minister Antonis Samaras and his finance minister had agreed the list of measures to be put to coalition party leaders and the European Union and IMF.
"There is a basic agreement (between party leaders), we're moving forward to the final negotiations," Finance Minister Yannis Stournaras told reporters after a meeting of the three leaders in Samaras' conservative-led government.
One of the three leaders, Fotis Kouvelis warned that sticking points remained.
"There was agreement on the basic framework. There are outstanding issues," said Kouvelis, head of the moderate Democratic Left party.
Neither Stournaras nor Kouvelis specified what issues the party chiefs had made progress on and whether the deal on a "basic framework" went beyond a similar broad agreement they said they had notched up a month ago.
The coalition has been haggling for weeks over the package demanded by international lenders keeping the country afloat, with Samaras's allies sharply opposed to across-the-board cuts in wages and pensions as well as plans to fire civil servants.
Pressure is growing on the party chiefs to strike a deal of some sort before the troika of European Commission, European Central Bank and the International Monetary Fund return to Athens early next week.
The troika's blessing of the package is a pre-requisite for Greece to secure its next round of bailout cash, without which the country faces certain bankruptcy and a potentially disastrous euro zone exit.
Kouvelis and Samaras's other ally, Socialist chief Evangelos Venizelos, are under rising pressure from their voter base to fight the austerity package, which includes a new round of wage, pension and welfare benefit cuts.
On Wednesday, nearly 70,000 Greeks marched to parliament chanting "We won't submit to the troika (of lenders)" and "EU, IMF Out!" as part of a general strike against the cuts.
(Reporting by Lefteris Papadimas, Writing by Deepa Babington; editing by Patrick Graham)
Source: http://news.yahoo.com/greek-party-chiefs-inch-forward-austerity-cuts-113258518--business.html
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UNITED NATIONS (Reuters) - Egypt opposes foreign military intervention to stop the civil war in Syria and prefers an inclusive, negotiated settlement, Egypt's new Islamist president, Mohamed Mursi, said on Wednesday.
"Egypt is committed to pursue the sincere efforts it has been exerting to put an end to the catastrophe in Syria within an Arab, regional and international framework," Mursi said in his first speech to the U.N. General Assembly.
Such a solution should be "one that preserves the unity of this brotherly state, involves all factions of the Syrian people without racial, religious or sectarian discrimination and spares Syria the dangers of foreign military intervention that we oppose," he said.
Mursi's comments contrasted with those of Qatari leader Emir Sheikh Hamad bin Khalifa al-Thani, who called on Arab countries on Tuesday to bypass the U.N. Security Council and intervene directly to stop the bloodshed in Syria.
Mursi has been outspoken about Syria since he took office on June 30. He has described Syrian President Bashar al-Assad's government as "oppressive" and said it is necessary to support the Syrian people.
"We will continue to work to put an end to the suffering of the Syrian people and provide them an opportunity to choose freely that regime that best represents them," Mursi said.
However, the Islamist president canceled a meeting of four regional powers on the Syria crisis - Egypt, Iran, Turkey and Saudi Arabia - planned for this week due to the absence of Turkey's prime minister from the U.N. General Assembly.
In the wake of anti-U.S. protests in Egypt and other Muslim countries sparked by a video made in California insulting to the Prophet Mohammad, Mursi called for increased understanding and "respect" of cultural and religious beliefs.
"What Muslims and migrants are going through in a number of regions worldwide, in terms of discrimination and violation of their human rights ... is unacceptable," he said.
"These practices have become pervasive enough that they now carry a name: 'Islamophobia,'" he added.
"Egypt respects freedom of expression, one that is not used to incite hatred against anyone," said Mursi, echoing comments to the assembly by several other leaders of Muslim countries.
On Tuesday, U.S. President Barack Obama condemned the violence sparked by the video, which depicts the Prophet Mohammad as a womanizer, fool and child abuser. But he stressed that the U.S. government had nothing to do with its production and staunchly defended free speech.
(Reporting By Amena Bakr and Arshad Mohammed; Editing by David Brunnstrom and Will Dunham)
Source: http://news.yahoo.com/egypts-mursi-says-opposes-foreign-intervention-syria-165353007.html
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Iranian President Mahmoud Ahmadinejad speaks during an exclusive interview with Associated Press editorial staff during his visit to the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
Iranian President Mahmoud Ahmadinejad speaks during an exclusive interview with Associated Press editorial staff during his visit to the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
Iranian President Mahmoud Ahmadinejad speaks during an exclusive interview with Associated Press editorial staff during his visit to the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
Iranian President Mahmoud Ahmadinejad speaks during an exclusive interview with Associated Press editorial staff during his visit to the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
Iranian President Mahmoud Ahmadinejad listens during an exclusive interview with Associated Press editorial staff during his visit for the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
Iranian President Mahmoud Ahmadinejad, center, and Iranian government officials, left, hold an exclusive interview with Associated Press editorial staff, right, during his visit for the 67th session of the United Nations General Assembly on Tuesday, Sept. 25, 2012 in New York. (AP Photo/Bebeto Matthews)
NEW YORK (AP) ? Iranian President Mahmoud Ahmadinejad said Tuesday that a new world order needs to emerge, away from years of American "bullying" and domination.
Ahmadinejad spoke to The Associated Press in a wide-ranging interview on the sidelines of the U.N. General Assembly ? his last as president of Iran.
He also discussed solutions for Syria, dismissed the question of Iran's nuclear ambition and claimed that despite Western sanctions his country is better off than it was when he took office in 2005.
"God willing, a new order will come together and we'll do away with everything that distances us," Ahmadinejad said. "Now even elementary school kids throughout the world have understood that the United States government is following an international policy of bullying. They command from behind the microphone. They command and impose their wills on how things should be done. I do believe the system of empires has reached the end of the road. The world can no longer see an emperor commanding it."
"Bullying must come to an end. Occupation must come to an end," he added.
Ahmadinejad said Iran was one of nearly a dozen countries forming a new contact group to try to end the 18-month-old civil war in Syria. The group would include '10 or 11 countries in the Middle East and elsewhere and meet in New York "very soon," Ahmadinejad said.
He said the group hopes to get government and the opposition to sit across from each other.
Activists say nearly 30,000 people have died in the Syrian uprising that began in the March 2011.
Earlier this month, Egyptian president Mohammed Morsi announced the formation of a four-member contact group with Iran, Turkey and Saudi Arabia. But Saudi Arabia so far has not participated.
It was unclear how Ahmadinejad's contact group would combine with the earlier effort by Morsi or mediating efforts of international envoy Lakhdar Brahimi.
He announced it ahead of a Friday meeting of key countries in the so-called Friends of Syria group, which supports the opposition and is planning for a transition after the departure of President Bashar Assad.
"I will do everything in my power to create stability, peace and understanding in Syria," Ahmadinejad said.
He denied any knowledge of the whereabouts of Robert Levinson, a private investigator and former FBI agent who vanished in Iran five years ago. He said he directed Iranian and intelligence services two years ago to work with their counterparts in the U.S. to locate him.
"And if any help there is that I can bring to bear, I would be happy to do so," he said.
____
Associated Press writers Maria Sanminiatelli and Christopher Chester contributed to this story.
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Gov. Mark Dayton
This year's annual governor's deer-hunting opener will be in Winona.
Gov. Mark Dayton will host a range of activities starting Nov. 2 to highlight the money that deer-hunting moves through the state economy. The firearms season opens Saturday, Nov. 3.
The tradition of the governor's deer opener was begun by former Gov. Tim Pawlenty. This year's is the 10th annual.
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'Modern Family' and 'Game Change' also win big at ceremony hosted by Jimmy Kimmel.
By Amy Wilkinson
Damian Lewis of "Homeland" with his Emmy for Outstanding Lead Actor
Photo: Getty Images
Source: http://www.mtv.com/news/articles/1694288/emmys-2012-homeland.jhtml
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Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
LA JOLLA, Calif., September 25, 2012 The process researchers use to generate induced pluripotent stem cells (iPSCs)a special type of stem cell that can be made in the lab from any type of adult cellis time consuming and inefficient. To speed things up, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) turned to kinase inhibitors. These chemical compounds block the activity of kinases, enzymes responsible for many aspects of cellular communication, survival, and growth. As they outline in a paper published September 25 in Nature Communications, the team found several kinase inhibitors that, when added to starter cells, help generate many more iPSCs than the standard method. This new capability will likely speed up research in many fields, better enabling scientists around the world to study human disease and develop new treatments.
"Generating iPSCs depends on the regulation of communication networks within cells," explained Tariq Rana, Ph.D., program director in Sanford-Burnham's Sanford Children's Health Research Center and senior author of the study. "So, when you start manipulating which genes are turned on or off in cells to create pluripotent stem cells, you are probably activating a large number of kinases. Since many of these active kinases are likely inhibiting the conversion to iPSCs, it made sense to us that adding inhibitors might lower the barrier."
According to Tony Hunter, Ph.D., professor in the Molecular and Cell Biology Laboratory at the Salk Institute for Biological Studies and director of the Salk Institute Cancer Center, "The identification of small molecules that improve the efficiency of generating iPSCs is an important step forward in being able to use these cells therapeutically. Tariq Rana's exciting new work has uncovered a class of protein kinase inhibitors that override the normal barriers to efficient iPSC formation, and these inhibitors should prove useful in generating iPSCs from new sources for experimental and ultimately therapeutic purposes." Hunter, a kinase expert, was not involved in this study.
The promise of iPSCs
At the moment, the only treatment option available to many heart failure patients is a heart transplant. Looking for a better alternative, many researchers are coaxing stem cells into new heart muscle. In Alzheimer's disease, researchers are also interested in stem cells, using them to reproduce a person's own malfunctioning brain cells in a dish, where they can be used to test therapeutic drugs. But where do these stem cells come from? Since the advent of iPSC technology, the answer in many cases is the lab. Like their embryonic cousins, iPSCs can be used to generate just about any cell typeheart, brain, or muscle, to name a fewthat can be used to test new therapies or potentially to replace diseased or damaged tissue.
It sounds simple enough: you start with any type of differentiated cell, such as skin cells, add four molecules that reprogram the cells' genomes, and then try to catch those that successfully revert to unspecialized iPSCs. But the process takes a long time and isn't very efficientyou can start with thousands of skin cells and end up with just a few iPSCs.
Inhibiting kinases to make more iPSCs
Zhonghan Li, a graduate student in Rana's laboratory, took on the task of finding kinase inhibitors that might speed up the iPSC-generating process. Scientists in the Conrad Prebys Center for Chemical Genomics, Sanford-Burnham's drug discovery facility, provided Li with a collection of more than 240 chemical compounds that inhibit kinases. Li painstakingly added them one-by-one to his cells and waited to see what happened. Several kinase inhibitors produced many more iPSCs than the untreated cellsin some cases too many iPSCs for the tiny dish housing them. The most potent inhibitors targeted three kinases in particular: AurkA, P38, and IP3K.
Working with the staff in Sanford-Burnham's genomics, bioinformatics, animal modeling, and histology core facilitiesvaluable resources and expertise available to all Sanford-Burnham scientists and the scientific community at largeRana and Li further confirmed the specificity of their findings and even nailed down the mechanism behind one inhibitor's beneficial actions.
"We found that manipulating the activity of these kinases can substantially increase cellular reprogramming efficiency," Rana said. "But what's more, we've also provided new insights into the molecular mechanism of reprogramming and revealed new functions for these kinases. We hope these findings will encourage further efforts to screen for small molecules that might prove useful in iPSC-based therapies."
###
Note to members of the media: Please contact Heather Buschman at hbuschman@sanfordburnham.org to schedule on-site, phone, or Skype interviews with Tariq Rana, Ph.D. Images are also available upon request.
About Sanford-Burnham Medical Research Institute
Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. The Institute consistently ranks among the top five organizations worldwide for its scientific impact in the fields of biology and biochemistry (defined by citations per publication) and currently ranks third in the nation in NIH funding among all laboratory-based research institutes. Sanford-Burnham utilizes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies. Sanford-Burnham is a U.S.-based, non-profit public benefit corporation, with operations in San Diego (La Jolla), California and Orlando (Lake Nona), Florida. For more information, news, and events, please visit us at sanfordburnham.org.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Heather Buschman
hbuschman@sanfordburnham.org
858-795-5343
Sanford-Burnham Medical Research Institute
LA JOLLA, Calif., September 25, 2012 The process researchers use to generate induced pluripotent stem cells (iPSCs)a special type of stem cell that can be made in the lab from any type of adult cellis time consuming and inefficient. To speed things up, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) turned to kinase inhibitors. These chemical compounds block the activity of kinases, enzymes responsible for many aspects of cellular communication, survival, and growth. As they outline in a paper published September 25 in Nature Communications, the team found several kinase inhibitors that, when added to starter cells, help generate many more iPSCs than the standard method. This new capability will likely speed up research in many fields, better enabling scientists around the world to study human disease and develop new treatments.
"Generating iPSCs depends on the regulation of communication networks within cells," explained Tariq Rana, Ph.D., program director in Sanford-Burnham's Sanford Children's Health Research Center and senior author of the study. "So, when you start manipulating which genes are turned on or off in cells to create pluripotent stem cells, you are probably activating a large number of kinases. Since many of these active kinases are likely inhibiting the conversion to iPSCs, it made sense to us that adding inhibitors might lower the barrier."
According to Tony Hunter, Ph.D., professor in the Molecular and Cell Biology Laboratory at the Salk Institute for Biological Studies and director of the Salk Institute Cancer Center, "The identification of small molecules that improve the efficiency of generating iPSCs is an important step forward in being able to use these cells therapeutically. Tariq Rana's exciting new work has uncovered a class of protein kinase inhibitors that override the normal barriers to efficient iPSC formation, and these inhibitors should prove useful in generating iPSCs from new sources for experimental and ultimately therapeutic purposes." Hunter, a kinase expert, was not involved in this study.
The promise of iPSCs
At the moment, the only treatment option available to many heart failure patients is a heart transplant. Looking for a better alternative, many researchers are coaxing stem cells into new heart muscle. In Alzheimer's disease, researchers are also interested in stem cells, using them to reproduce a person's own malfunctioning brain cells in a dish, where they can be used to test therapeutic drugs. But where do these stem cells come from? Since the advent of iPSC technology, the answer in many cases is the lab. Like their embryonic cousins, iPSCs can be used to generate just about any cell typeheart, brain, or muscle, to name a fewthat can be used to test new therapies or potentially to replace diseased or damaged tissue.
It sounds simple enough: you start with any type of differentiated cell, such as skin cells, add four molecules that reprogram the cells' genomes, and then try to catch those that successfully revert to unspecialized iPSCs. But the process takes a long time and isn't very efficientyou can start with thousands of skin cells and end up with just a few iPSCs.
Inhibiting kinases to make more iPSCs
Zhonghan Li, a graduate student in Rana's laboratory, took on the task of finding kinase inhibitors that might speed up the iPSC-generating process. Scientists in the Conrad Prebys Center for Chemical Genomics, Sanford-Burnham's drug discovery facility, provided Li with a collection of more than 240 chemical compounds that inhibit kinases. Li painstakingly added them one-by-one to his cells and waited to see what happened. Several kinase inhibitors produced many more iPSCs than the untreated cellsin some cases too many iPSCs for the tiny dish housing them. The most potent inhibitors targeted three kinases in particular: AurkA, P38, and IP3K.
Working with the staff in Sanford-Burnham's genomics, bioinformatics, animal modeling, and histology core facilitiesvaluable resources and expertise available to all Sanford-Burnham scientists and the scientific community at largeRana and Li further confirmed the specificity of their findings and even nailed down the mechanism behind one inhibitor's beneficial actions.
"We found that manipulating the activity of these kinases can substantially increase cellular reprogramming efficiency," Rana said. "But what's more, we've also provided new insights into the molecular mechanism of reprogramming and revealed new functions for these kinases. We hope these findings will encourage further efforts to screen for small molecules that might prove useful in iPSC-based therapies."
###
Note to members of the media: Please contact Heather Buschman at hbuschman@sanfordburnham.org to schedule on-site, phone, or Skype interviews with Tariq Rana, Ph.D. Images are also available upon request.
About Sanford-Burnham Medical Research Institute
Sanford-Burnham Medical Research Institute is dedicated to discovering the fundamental molecular causes of disease and devising the innovative therapies of tomorrow. The Institute consistently ranks among the top five organizations worldwide for its scientific impact in the fields of biology and biochemistry (defined by citations per publication) and currently ranks third in the nation in NIH funding among all laboratory-based research institutes. Sanford-Burnham utilizes a unique, collaborative approach to medical research and has established major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute is especially known for its world-class capabilities in stem cell research and drug discovery technologies. Sanford-Burnham is a U.S.-based, non-profit public benefit corporation, with operations in San Diego (La Jolla), California and Orlando (Lake Nona), Florida. For more information, news, and events, please visit us at sanfordburnham.org.
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-09/smri-mie092112.php
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'I had such fun playing that character,' she tells MTV News about Melina Matsoukas-directed video.
By Jocelyn Vena, with reporting by Ryan J. Downey
Christina Aguilera in her "Your Body" music video
Photo: RCA/ Sony Music Entertainment
Source: http://www.mtv.com/news/articles/1694354/christina-aguilera-your-body-bad-girl.jhtml
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